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Cardio Program of Excellence in Glycosciences

Upcoming Seminars

Cardio PEG Lab Meetings

(Physiology 612, 9.30-11)

This meeting is suspended over the summer. Watch this space for updates.

Cardio PEG Retreat

(Mt Washington Conference Center)

July 15th, Register by July 5th @ CardioPEG Registration

Schedule: Final Rev PEG 2016 Retreat Sched[1].pdfFinal Rev PEG 2016 Retreat Sched[1].pdf

Glycobiology Interest Group

This meeting is suspended over the summer. Watch this space for updates.

Upcoming Classwork

January 2017: Fundamentals of Glycobiology

July 2017: Techniques in Glycobiology

D: Myocyte Isolation and Myocyte and Cardiac Physiology

Synopsis: This Core provides a critical link between glycoscientists and cardiologists and is key to the completion of all projects. The Cardiac and Myocyte Physiology Core is to provides: 1) isolation of adult and neonatal myocytes from rodent models, and physiologic analysis of myocyte systolic and diastolic function; 2) in vivo analysis of cardiovascular function based on non-invasive echo Doppler imaging; 3) comprehensive in vivo cardiac chamber functional analysis using pressure-volume relationships; 4) generation of infarction and preconditioning in isolated heart models and functional assessment in these models by Langendorff preparation; 5) steady-state force-calcium dependence in isolated skinned muscle trabeculae; 6) motoring reactive oxygen species (ROS) production by EPR, both in isolated cells and whole tissue levels; and 7) assessing the involvement of highly reactive cysteines in the biological action of several ROS and reactive nitrogen species (RNS).

Consultation and collaborations with the PEGs and community will be available.

David A. Kass, M.D.

Abraham and Virginia Weiss Professor of Cardiology
Professor of Medicine and Biomedical Engineering
Division of Cardiology
The Johns Hopkins University School of Medicine
Ross 858
720 Rutland Avenue, Baltimore,MD

Phone: 410-955-7153
Fax: 410-502-2558

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