The Glycoconjugates and Cardiovascular Disease PEG is comprised of 5 projects, a Shared Resources Core, and an Educational Core.
Project 1: Crosstalk Between O-GlcNAcylation and Phosphorylation in Diabetic Cardiomyopathy.
PI Gerald W. Hart
Project 2: O-GlcNAc and Cardioprotection.
PI Natasha E. Zachara
Project 3: Glycoprotein involvement in cardiac fibroblast-myocyte communication.
PI Jenny Van Eyk, co-PI David Graham
Project 4: Roles of Platelet Glycoproteins and Glycans on Platelet Reactivity and Cardiovascular Disease.
PI Hui Zhang
Project 5: Glycosphingolipids ,Glycosyltransferases and Cardiovascular disease.
PI Subroto Chatterjee
The Education Core is providing three courses, with both didactic and hands on training, which are designed to train future leaders in glycoscience research.
Research Cores: The goal of the research cores is to support projects in the PEG and to support projects in the research community whose goals are closely aligned with those of the NHLBI.